AMANITA BLOG
All about Amanita muscaria and other nootropic mushrooms
How muscimol works?
Muscimol in Amanita muscaria
Muscimol - one of the main active ingredients of Fly agaric.

— After conducting research on the effects of muscimol, Bulgarian scientists found that it is a powerful active stimulant of a key brain receptor that calms you down - GABA receptors, muscimol works with a specific subtype of this receptor.

— Genetic tests have found several subtypes of Gaba receptors, and muscimol has a specific effect on one of them that sets the tone for the brain, and for this reason, Amanita muscaria may have been used for thousands of years to help people stay calm and deal with stress.

— The study was conducted to identify the neuroprotective role of fly agaric extracts in relation to some neurodegenerative diseases such as Parkinson's and Alzheimer's diseases, their powerful role in the treatment of cerebral ischemia and other socially significant conditions health, provided the basis for this review.

— The findings suggest that Amanita muscaria (Amanita muscaria) has a wide variety of beneficial effects in cell protection and especially in neuroprotection, cardioprotection, hepatoprotection and protection against oxidative stress.

— In terms of effects on memory, intra-hippocampal administration of muscimol significantly increased the percentage of neurons active in cornus amonius, improving the learning and memory abilities of rats in both normal and Alzheimer's rats, suggesting that intensification of GABAergic processes may be a useful pharmacotherapeutic strategy for early memory loss in Alzheimer's.


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